Literature summary for 6.5.1.B1 extracted from

Greer, C.L.; Javor, B.; Abelson, J.
RNA ligase in bacteria: formation of a 2',5' linkage by an Escherichia coli extract (1983), Cell, 33, 899-906.

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Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3'-half-tRNA molecule with a 5'-OH end + 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end	the reaction occurs possible through a one-step reaction involving hydrolysis of the 2',3'-cyclic phosphodiester bond and the simultaneous formation of a 2'-5'-phosphodiester bond. The reaction proceeds without added ATP or NAD+	Escherichia coli	mature tRNA molecule containing a 2'-5'-phosphodiester bond	-	?

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Release 2023.1 (January 2023)