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Literature summary for 6.5.1.4 extracted from

  • Filipowicz, W.
    RNA 3-terminal phosphate cyclases and cyclase-like proteins (2016), Postepy Biochem., 62, 327-334 .
    View publication on PubMed
Search for more literature for 6.5.1.4

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + [RNA 3'-phosphate cyclase]-L-histidine Escherichia coli
-
 [RNA 3'-phosphate cyclase]-Ntau-(5'-adenylyl)-L-histidine + diphosphate
-
 ?
ATP + [RNA 3'-phosphate cyclase]-L-histidine Homo sapiens
-
 [RNA 3'-phosphate cyclase]-Ntau-(5'-adenylyl)-L-histidine + diphosphate
-
 ?
ATP + [RNA]-3'-(3'-phospho-ribonucleoside) Escherichia coli
-
 AMP + diphosphate + [RNA]-3'-(2',3'-cyclophospho)-ribonucleoside
-
 ?
ATP + [RNA]-3'-(3'-phospho-ribonucleoside) Homo sapiens
-
 AMP + diphosphate + [RNA]-3'-(2',3'-cyclophospho)-ribonucleoside
-
 ?
[RNA 3'-phosphate cyclase]-Ntau-(5'-adenylyl)-L-histidine + [RNA]-3'-(3'-phospho-ribonucleoside) Escherichia coli
-
 [RNA 3'-phosphate cyclase]-L-histidine + [RNA]-3'-ribonucleoside-3'-(5'-diphosphoadenosine)
-
 ?
[RNA 3'-phosphate cyclase]-Ntau-(5'-adenylyl)-L-histidine + [RNA]-3'-(3'-phospho-ribonucleoside) Homo sapiens
-
 [RNA 3'-phosphate cyclase]-L-histidine + [RNA]-3'-ribonucleoside-3'-(5'-diphosphoadenosine)
-
 ?
[RNA]-3'-ribonucleoside-3'-(5'-diphosphoadenosine) Escherichia coli
-
 [RNA]-3'-(2',3'-cyclophospho)-ribonucleoside + AMP
-
 ?
[RNA]-3'-ribonucleoside-3'-(5'-diphosphoadenosine) Homo sapiens
-
 [RNA]-3'-(2',3'-cyclophospho)-ribonucleoside + AMP
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + [RNA 3'-phosphate cyclase]-L-histidine
-
 Escherichia coli [RNA 3'-phosphate cyclase]-Ntau-(5'-adenylyl)-L-histidine + diphosphate
-
 ?
ATP + [RNA 3'-phosphate cyclase]-L-histidine
-
 Homo sapiens [RNA 3'-phosphate cyclase]-Ntau-(5'-adenylyl)-L-histidine + diphosphate
-
 ?
ATP + [RNA]-3'-(3'-phospho-ribonucleoside)
-
 Escherichia coli AMP + diphosphate + [RNA]-3'-(2',3'-cyclophospho)-ribonucleoside
-
 ?
ATP + [RNA]-3'-(3'-phospho-ribonucleoside)
-
 Homo sapiens AMP + diphosphate + [RNA]-3'-(2',3'-cyclophospho)-ribonucleoside
-
 ?
additional information the enzyme is incapable of phosphodiester synthesis (i.e., ligation) following adenylation of the 5'-terminal phosphate Escherichia coli ?
-
 ?
additional information the enzyme is incapable of phosphodiester synthesis (i.e., ligation) following adenylation of the 5'-terminal phosphate Homo sapiens ?
-
 ?
[RNA 3'-phosphate cyclase]-Ntau-(5'-adenylyl)-L-histidine + [RNA]-3'-(3'-phospho-ribonucleoside)
-
 Escherichia coli [RNA 3'-phosphate cyclase]-L-histidine + [RNA]-3'-ribonucleoside-3'-(5'-diphosphoadenosine)
-
 ?
[RNA 3'-phosphate cyclase]-Ntau-(5'-adenylyl)-L-histidine + [RNA]-3'-(3'-phospho-ribonucleoside)
-
 Homo sapiens [RNA 3'-phosphate cyclase]-L-histidine + [RNA]-3'-ribonucleoside-3'-(5'-diphosphoadenosine)
-
 ?
[RNA]-3'-ribonucleoside-3'-(5'-diphosphoadenosine)
-
 Escherichia coli [RNA]-3'-(2',3'-cyclophospho)-ribonucleoside + AMP
-
 ?
[RNA]-3'-ribonucleoside-3'-(5'-diphosphoadenosine)
-
 Homo sapiens [RNA]-3'-(2',3'-cyclophospho)-ribonucleoside + AMP
-
 ?

Synonyms

Synonyms Comment Organism
RNA 3'-terminal phosphate cyclase
-
 Escherichia coli
RNA 3'-terminal phosphate cyclase
-
 Homo sapiens
RtcA
-
 Escherichia coli
RtcA
-
 Homo sapiens