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Literature summary for 6.5.1.4 extracted from

  • Zhelkovsky, A.M.; McReynolds, L.A.
    Polynucleotide 3-terminal phosphate modifications by RNA and DNA ligases (2014), J. Biol. Chem., 289, 33608-33616 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.5.1.4

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + [RNA 3'-phosphate cyclase]-L-histidine Methanothermobacter thermautotrophicus
-
 [RNA 3'-phosphate cyclase]-Ntau-(5'-adenylyl)-L-histidine + diphosphate
-
 ?
ATP + [RNA]-3'-(3'-phospho-ribonucleoside) Methanothermobacter thermautotrophicus
-
 AMP + diphosphate + [RNA]-3'-(2',3'-cyclophospho)-ribonucleoside
-
 ?
[RNA 3'-phosphate cyclase]-Ntau-(5'-adenylyl)-L-histidine + [RNA]-3'-(3'-phospho-ribonucleoside) Methanothermobacter thermautotrophicus
-
 [RNA 3'-phosphate cyclase]-L-histidine + [RNA]-3'-ribonucleoside-3'-(5'-diphosphoadenosine)
-
 ?
[RNA]-3'-ribonucleoside-3'-(5'-diphosphoadenosine) Methanothermobacter thermautotrophicus
-
 [RNA]-3'-(2',3'-cyclophospho)-ribonucleoside + AMP
-
 ?

Organism

Organism UniProt Comment Textmining
Methanothermobacter thermautotrophicus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + [RNA 3'-phosphate cyclase]-L-histidine
-
 Methanothermobacter thermautotrophicus [RNA 3'-phosphate cyclase]-Ntau-(5'-adenylyl)-L-histidine + diphosphate
-
 ?
ATP + [RNA]-3'-(3'-phospho-ribonucleoside)
-
 Methanothermobacter thermautotrophicus AMP + diphosphate + [RNA]-3'-(2',3'-cyclophospho)-ribonucleoside
-
 ?
additional information the enzyme is also able to convert DNA-3'-phosphate to single-stranded DNA-3'-diphosphate-5'-adenylate but not able to modify a 3'-phosphate in nicked double-stranded DNA Methanothermobacter thermautotrophicus ?
-
 ?
[RNA 3'-phosphate cyclase]-Ntau-(5'-adenylyl)-L-histidine + [RNA]-3'-(3'-phospho-ribonucleoside)
-
 Methanothermobacter thermautotrophicus [RNA 3'-phosphate cyclase]-L-histidine + [RNA]-3'-ribonucleoside-3'-(5'-diphosphoadenosine)
-
 ?
[RNA]-3'-ribonucleoside-3'-(5'-diphosphoadenosine)
-
 Methanothermobacter thermautotrophicus [RNA]-3'-(2',3'-cyclophospho)-ribonucleoside + AMP
-
 ?

Synonyms

Synonyms Comment Organism
RNL
-
 Methanothermobacter thermautotrophicus