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Literature summary for 6.5.1.3 extracted from

  • Rusche, L.N.; Cruz-Reyes, J.; Piller, K.J.; Sollner-Webb, B.
    Purification of a functional enzymatic editing complex from Trypanosoma brucei mitochondria (1997), EMBO J., 16, 4069-4081.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Trypanosoma brucei 5739
-

Organism

Organism UniProt Comment Textmining
Trypanosoma brucei
-
-
-

Purification (Commentary)

Purification (Comment) Organism
a complex with 4 activities predicted to catalyze RNA editing: gRNA-directed endonuclease, terminal uridyl transferase, 3' U-specific endonuclease, RNA ligase Trypanosoma brucei

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (ribonucleotide)n + (ribonucleotide)m
-
Trypanosoma brucei AMP + diphosphate + (ribonucleotide)n+m
-
?

Subunits

Subunits Comment Organism
More complex with 4 activities predicted to catalyze RNA editing: gRNA-directed endonuclease, terminal uridyl transferase, 3' U-specific endonuclease, RNA ligase. The complex is composed of 8 major polypeptides, three of which represent RNA ligase Trypanosoma brucei