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Literature summary for 6.5.1.1 extracted from

  • Cannone, G.; Xu, Y.; Beattie, T.; Bell, S.; Spagnolo, L.
    The architecture of an Okazaki fragment-processing holoenzyme from the archaeon Sulfolobus solfataricus (2015), Biochem. J., 465, 239-245 .
    View publication on PubMed
Search for more literature for 6.5.1.1

Activating Compound

Activating Compound Comment Organism Structure
proliferating cell nuclear antigen
-
 Saccharolobus solfataricus

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Rosetta (DE3) cells Saccharolobus solfataricus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m Saccharolobus solfataricus
-
 (deoxyribonucleotide)n+m + AMP + diphosphate
-
 ?
ATP + [DNA ligase]-L-lysine Saccharolobus solfataricus
-
 [DNA ligase]-N6-(5'-adenylyl)-L-lysine + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus Q980T8
-
-

Purification (Commentary)

Purification (Comment) Organism
HisTrap column chromatography, and Superose 10/300 gel filtration Saccharolobus solfataricus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m
-
 Saccharolobus solfataricus (deoxyribonucleotide)n+m + AMP + diphosphate
-
 ?
ATP + [DNA ligase]-L-lysine
-
 Saccharolobus solfataricus [DNA ligase]-N6-(5'-adenylyl)-L-lysine + diphosphate
-
 ?

Synonyms

Synonyms Comment Organism
ATP-dependent DNA ligase 1
-
 Saccharolobus solfataricus
LIG1
-
 Saccharolobus solfataricus
ligase 1
-
 Saccharolobus solfataricus