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Literature summary for 6.5.1.1 extracted from

  • Meier, T.I.; Yan, D.; Peery, R.B.; McAllister, K.A.; Zook, C.; Peng, S.B.; Zhao, G.
    Identification and characterization of an inhibitor specific to bacterial NAD+-dependent DNA ligases (2008), FEBS J., 275, 5258-5271.
    View publication on PubMed
Search for more literature for 6.5.1.1

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21 (DE3) cells Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information not inhibited by 2,4-diamino-7-dimethylamino-pyrimido[4,5-d]pyrimidine, trimethoprim, and methotrexate Homo sapiens
additional information not inhibited by 2,4-diamino-7-dimethylamino-pyrimido[4,5-d]pyrimidine, trimethoprim, and methotrexate Tequatrovirus T4

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Tequatrovirus T4
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Sepharose column chromatography and hydroxyapatite column chromatography Homo sapiens
Sepharose column chromatography and hydroxyapatite column chromatography Tequatrovirus T4

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
-
 Homo sapiens AMP + diphosphate + (deoxyribonucleotide)n+m
-
 ?
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
-
 Tequatrovirus T4 AMP + diphosphate + (deoxyribonucleotide)n+m
-
 ?

Synonyms

Synonyms Comment Organism
ATP-dependent DNA ligase
-
 Homo sapiens
Lig I
-
 Homo sapiens
T4 DNA ligase
-
 Tequatrovirus T4

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens
ATP
-
 Tequatrovirus T4