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Literature summary for 6.5.1.1 extracted from

  • Ciarrocchi, G.; Lestingi, M.; Fontana, M.; Spadari, S.; Montecuccho, A.
    Correlation between anthracycline structure and human DNA ligase inhibition (1991), Biochem. J., 279, 141-146.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
Anthracycline derivatives the inhibitors possessing a 3'-amino-4'-deoxy-sugar carrying no other modifications exhibit the most potent inhibition Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
-
Homo sapiens AMP + diphosphate + (deoxyribonucleotide)n+m
-
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