Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2R)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-(2-methyl-4-propoxyphenyl)piperazine | - |
Homo sapiens | |
(2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-(2-methyl-4-phenoxyphenyl)piperazine | - |
Homo sapiens | |
(2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-(2-methyl-4-propoxyphenyl)piperazine | - |
Homo sapiens | |
(2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-(4-propoxyphenyl)piperazine | - |
Homo sapiens | |
(2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-[2-methyl-4-(propan-2-yloxy)phenyl]piperazine | - |
Homo sapiens | |
(2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-[2-methyl-4-(trifluoromethoxy)phenyl]piperazine | - |
Homo sapiens | |
(2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-[4-propoxy-2-(trifluoromethyl)phenyl]piperazine | - |
Homo sapiens | |
(2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-4-(2-methyl-4-propoxyphenyl)-2-(propan-2-yl)piperazine | - |
Homo sapiens | |
(2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-4-(4-methoxy-2-methylphenyl)-2-methylpiperazine | - |
Homo sapiens | |
(2S)-1-[5-(1,1-difluoroethyl)-1,2,4-oxadiazol-3-yl]-4-(4-ethoxy-2-methylphenyl)-2-methylpiperazine | - |
Homo sapiens | |
(2S)-1-[5-(1,1-difluoroethyl)-1,2,4-oxadiazol-3-yl]-4-(5-ethoxy-3-methylpyridin-2-yl)-2-methylpiperazine | - |
Homo sapiens | |
(2S)-2-ethyl-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-4-(2-methyl-4-propoxyphenyl)piperazine | - |
Homo sapiens | |
(2S)-4-(2-chloro-4-propoxyphenyl)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methylpiperazine | - |
Homo sapiens | |
(2S)-4-(4-ethoxy-2-methylphenyl)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methylpiperazine | - |
Homo sapiens | |
(2S)-4-(5-ethoxy-3-methylpyridin-2-yl)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methylpiperazine | - |
Homo sapiens | |
(2S)-4-(6-ethoxy-4-methylpyridin-3-yl)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methylpiperazine | - |
Homo sapiens | |
1-(5-ethyl-1,2,4-oxadiazol-3-yl)-4-(2-methyl-4-propoxyphenyl)-2-(trifluoromethyl)piperazine | - |
Homo sapiens | |
1-(5-ethyl-1,2,4-oxadiazol-3-yl)-4-(2-methyl-4-propoxyphenyl)piperazine | - |
Homo sapiens | |
4-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-1-(4-propoxyphenyl)piperazine | - |
Homo sapiens | |
5-ethyl-3-(2'-methyl-4'-propoxybiphenyl-4-yl)-1,2,4-oxadiazole | - |
Homo sapiens | |
5-ethyl-3-(4'-propoxybiphenyl-4-yl)-1,2,4-oxadiazole | - |
Homo sapiens | |
N-(1-[3-[(2S)-4-(4-ethoxy-2-methylphenyl)-2-methylpiperazin-1-yl]-1,2,4-oxadiazol-5-yl]cyclobutyl)acetamide | - |
Homo sapiens | |
N-(2-[3-[(2S)-4-(4-ethoxy-2-methylphenyl)-2-methylpiperazin-1-yl]-1,2,4-oxadiazol-5-yl]propan-2-yl)acetamide | - |
Homo sapiens | |
N-([3-[(2S)-4-(4-ethoxy-2-methylphenyl)-2-methylpiperazin-1-yl]-1,2,4-oxadiazol-5-yl]methyl)acetamide | - |
Homo sapiens | |
N-[(1R)-1-[3-[(2S)-4-(4-ethoxy-2-methylphenyl)-2-methylpiperazin-1-yl]-1,2,4-oxadiazol-5-yl]ethyl]acetamide | - |
Homo sapiens | |
N-[(1S)-1-[3-[(2S)-4-(4-ethoxy-2-methylphenyl)-2-methylpiperazin-1-yl]-1,2,4-oxadiazol-5-yl]ethyl]acetamide | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Homo sapiens | Q13085 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
ACC1 | - |
Homo sapiens |
ACC2 | - |
Homo sapiens |
acetyl-CoA carboxylase | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000024 | - |
pH and temperature not specified in the publication | Homo sapiens | N-[(1S)-1-[3-[(2S)-4-(4-ethoxy-2-methylphenyl)-2-methylpiperazin-1-yl]-1,2,4-oxadiazol-5-yl]ethyl]acetamide | |
0.000037 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-4-(4-ethoxy-2-methylphenyl)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methylpiperazine | |
0.00004 | - |
pH and temperature not specified in the publication | Homo sapiens | N-[(1R)-1-[3-[(2S)-4-(4-ethoxy-2-methylphenyl)-2-methylpiperazin-1-yl]-1,2,4-oxadiazol-5-yl]ethyl]acetamide | |
0.000054 | - |
pH and temperature not specified in the publication | Homo sapiens | N-(1-[3-[(2S)-4-(4-ethoxy-2-methylphenyl)-2-methylpiperazin-1-yl]-1,2,4-oxadiazol-5-yl]cyclobutyl)acetamide | |
0.000071 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-(2-methyl-4-propoxyphenyl)piperazine | |
0.000126 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-ethyl-3-(2'-methyl-4'-propoxybiphenyl-4-yl)-1,2,4-oxadiazole | |
0.000159 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-4-(6-ethoxy-4-methylpyridin-3-yl)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methylpiperazine | |
0.000166 | - |
pH and temperature not specified in the publication | Homo sapiens | 1-(5-ethyl-1,2,4-oxadiazol-3-yl)-4-(2-methyl-4-propoxyphenyl)-2-(trifluoromethyl)piperazine | |
0.000178 | - |
pH and temperature not specified in the publication | Homo sapiens | (2R)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-(2-methyl-4-propoxyphenyl)piperazine | |
0.000193 | - |
pH and temperature not specified in the publication | Homo sapiens | N-(1-[3-[(2S)-4-(4-ethoxy-2-methylphenyl)-2-methylpiperazin-1-yl]-1,2,4-oxadiazol-5-yl]cyclobutyl)acetamide | |
0.000227 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-1-[5-(1,1-difluoroethyl)-1,2,4-oxadiazol-3-yl]-4-(4-ethoxy-2-methylphenyl)-2-methylpiperazine | |
0.000231 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-2-ethyl-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-4-(2-methyl-4-propoxyphenyl)piperazine | |
0.000244 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-4-(2-chloro-4-propoxyphenyl)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methylpiperazine | |
0.000246 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-[4-propoxy-2-(trifluoromethyl)phenyl]piperazine | |
0.000258 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-4-(5-ethoxy-3-methylpyridin-2-yl)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methylpiperazine | |
0.000259 | - |
pH and temperature not specified in the publication | Homo sapiens | N-([3-[(2S)-4-(4-ethoxy-2-methylphenyl)-2-methylpiperazin-1-yl]-1,2,4-oxadiazol-5-yl]methyl)acetamide | |
0.000273 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-[2-methyl-4-(propan-2-yloxy)phenyl]piperazine | |
0.000335 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-4-(2-methyl-4-propoxyphenyl)-2-(propan-2-yl)piperazine | |
0.000348 | - |
pH and temperature not specified in the publication | Homo sapiens | N-(2-[3-[(2S)-4-(4-ethoxy-2-methylphenyl)-2-methylpiperazin-1-yl]-1,2,4-oxadiazol-5-yl]propan-2-yl)acetamide | |
0.000355 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-1-[5-(1,1-difluoroethyl)-1,2,4-oxadiazol-3-yl]-4-(5-ethoxy-3-methylpyridin-2-yl)-2-methylpiperazine | |
0.000386 | - |
pH and temperature not specified in the publication | Homo sapiens | N-[(1S)-1-[3-[(2S)-4-(4-ethoxy-2-methylphenyl)-2-methylpiperazin-1-yl]-1,2,4-oxadiazol-5-yl]ethyl]acetamide | |
0.000391 | - |
pH and temperature not specified in the publication | Homo sapiens | 1-(5-ethyl-1,2,4-oxadiazol-3-yl)-4-(2-methyl-4-propoxyphenyl)piperazine | |
0.000486 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-4-(4-methoxy-2-methylphenyl)-2-methylpiperazine | |
0.000492 | - |
pH and temperature not specified in the publication | Homo sapiens | 1-(5-ethyl-1,2,4-oxadiazol-3-yl)-4-(2-methyl-4-propoxyphenyl)-2-(trifluoromethyl)piperazine | |
0.000688 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-4-(2-chloro-4-propoxyphenyl)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methylpiperazine | |
0.000724 | - |
pH and temperature not specified in the publication | Homo sapiens | N-[(1R)-1-[3-[(2S)-4-(4-ethoxy-2-methylphenyl)-2-methylpiperazin-1-yl]-1,2,4-oxadiazol-5-yl]ethyl]acetamide | |
0.000789 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-(2-methyl-4-phenoxyphenyl)piperazine | |
0.000811 | - |
pH and temperature not specified in the publication | Homo sapiens | N-(2-[3-[(2S)-4-(4-ethoxy-2-methylphenyl)-2-methylpiperazin-1-yl]-1,2,4-oxadiazol-5-yl]propan-2-yl)acetamide | |
0.000841 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-ethyl-3-(4'-propoxybiphenyl-4-yl)-1,2,4-oxadiazole | |
0.001028 | - |
pH and temperature not specified in the publication | Homo sapiens | (2R)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-(2-methyl-4-propoxyphenyl)piperazine | |
0.00146 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-ethyl-3-(2'-methyl-4'-propoxybiphenyl-4-yl)-1,2,4-oxadiazole | |
0.00183 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-[2-methyl-4-(trifluoromethoxy)phenyl]piperazine | |
0.00191 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-(2-methyl-4-propoxyphenyl)piperazine | |
0.00258 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-(4-propoxyphenyl)piperazine | |
0.00393 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-2-ethyl-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-4-(2-methyl-4-propoxyphenyl)piperazine | |
0.00401 | - |
pH and temperature not specified in the publication | Homo sapiens | 1-(5-ethyl-1,2,4-oxadiazol-3-yl)-4-(2-methyl-4-propoxyphenyl)piperazine | |
0.00428 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-ethyl-3-(4'-propoxybiphenyl-4-yl)-1,2,4-oxadiazole | |
0.00457 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-4-(4-ethoxy-2-methylphenyl)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methylpiperazine | |
0.00909 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-4-(5-ethoxy-3-methylpyridin-2-yl)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methylpiperazine | |
0.00921 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-4-(6-ethoxy-4-methylpyridin-3-yl)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methylpiperazine | |
0.00936 | - |
pH and temperature not specified in the publication | Homo sapiens | (2S)-1-[5-(1,1-difluoroethyl)-1,2,4-oxadiazol-3-yl]-4-(4-ethoxy-2-methylphenyl)-2-methylpiperazine | |
0.01 | - |
value above, pH and temperature not specified in the publication | Homo sapiens | (2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-[2-methyl-4-(propan-2-yloxy)phenyl]piperazine | |
0.01 | - |
value above, pH and temperature not specified in the publication | Homo sapiens | (2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-(4-propoxyphenyl)piperazine | |
0.01 | - |
value above, pH and temperature not specified in the publication | Homo sapiens | 4-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-1-(4-propoxyphenyl)piperazine | |
0.01 | - |
value above, pH and temperature not specified in the publication | Homo sapiens | (2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-4-(2-methyl-4-propoxyphenyl)-2-(propan-2-yl)piperazine | |
0.01 | - |
value above, pH and temperature not specified in the publication | Homo sapiens | (2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-(2-methyl-4-phenoxyphenyl)piperazine | |
0.01 | - |
value above, pH and temperature not specified in the publication | Homo sapiens | (2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-[2-methyl-4-(trifluoromethoxy)phenyl]piperazine | |
0.01 | - |
value above, pH and temperature not specified in the publication | Homo sapiens | (2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-2-methyl-4-[4-propoxy-2-(trifluoromethyl)phenyl]piperazine | |
0.01 | - |
value above, pH and temperature not specified in the publication | Homo sapiens | (2S)-1-[5-(1,1-difluoroethyl)-1,2,4-oxadiazol-3-yl]-4-(5-ethoxy-3-methylpyridin-2-yl)-2-methylpiperazine | |
0.01 | - |
value above, pH and temperature not specified in the publication | Homo sapiens | N-([3-[(2S)-4-(4-ethoxy-2-methylphenyl)-2-methylpiperazin-1-yl]-1,2,4-oxadiazol-5-yl]methyl)acetamide | |
0.01 | - |
value above, pH and temperature not specified in the publication | Homo sapiens | (2S)-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-4-(4-methoxy-2-methylphenyl)-2-methylpiperazine |