Literature summary for 6.4.1.2 extracted from

Xiang, S.; Callaghan, M.M.; Watson, K.G.; Tong, L.
A different mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by tepraloxydim (2009), Proc. Natl. Acad. Sci. USA, 106, 20723-20727.

Cloned(Commentary)

Cloned (Comment)	Organism
cloning and expression of the CT domain comprising residues 1476-2233	Saccharomyces cerevisiae

Crystallization (Commentary)

Crystallization (Comment)	Organism
enzyme CT domain in complex with inhibitor tepraloxydim, hanging drop vapour diffusion method, at 4°C, 10 mg/ml protein in solution containing 0.1 M sodium citrate, pH 7.5, 8% w/v PEG 8000, 10% v/v glycerol, 5 mM tepraloxydim, and 5% v/v dimethyl sulfoxide, is mixed with reservoir solution containing 0.1 M sodium citrate, pH 5.5,8% w/v PEG 8000, and 10% v/v glycerol, X-ray diffraction structure determination and analysis at 2.3 A resolution	Saccharomyces cerevisiae

Crystallization (Comment)

Organism

enzyme CT domain in complex with inhibitor tepraloxydim, hanging drop vapour diffusion method, at 4°C, 10 mg/ml protein in solution containing 0.1 M sodium citrate, pH 7.5, 8% w/v PEG 8000, 10% v/v glycerol, 5 mM tepraloxydim, and 5% v/v dimethyl sulfoxide, is mixed with reservoir solution containing 0.1 M sodium citrate, pH 5.5,8% w/v PEG 8000, and 10% v/v glycerol, X-ray diffraction structure determination and analysis at 2.3 A resolution

Saccharomyces cerevisiae

Inhibitors

Inhibitors	Comment	Organism
CP-640186	-	Saccharomyces cerevisiae
Haloxyfop	a herbicide	Saccharomyces cerevisiae
tepraloxydim	a herbicide, binding mode and structure-activity relationship, molecular inhibition mechanism, overview	Saccharomyces cerevisiae

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	Q00955	-	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant CT domain comprising residues 1476-2233	Saccharomyces cerevisiae

Synonyms

Synonyms	Comment	Organism
ACC	-	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)