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Literature summary for 6.4.1.2 extracted from

  • Raymer, B.; Kavana, M.; Price, A.; Wang, B.; Corcoran, L.; Kulathila, R.; Groarke, J.; Mann, T.
    Synthesis and characterization of a BODIPY-labeled derivative of Soraphen A that binds to acetyl-CoA carboxylase (2009), Bioorg. Med. Chem. Lett., 19, 2804-2807.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
BODIPY-soraphen A a soraphen A derivative, shows high activity against ACC2, synthesis, overview. BODIPY-soraphen A directly binds to the BC domain of the ACC enzyme by causing a 10°C increase in thermal stability of the protein using a differential scanning calorimetry assay Homo sapiens
soraphen A
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Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O00763
-
-

Synonyms

Synonyms Comment Organism
ACC2
-
Homo sapiens