Activating Compound | Comment | Organism | Structure |
---|---|---|---|
citrate | barely detectable activity without citrate | Rattus norvegicus | |
citrate | barely detectable activity without citrate | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expressed in Sf9 cells | Rattus norvegicus |
expressed in Sf9 cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
malonyl-CoA | - |
Homo sapiens | |
palmitoyl-CoA | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.034 | - |
acetyl-CoA | at 37°C | Homo sapiens | |
0.037 | - |
acetyl-CoA | at 37°C | Rattus norvegicus | |
0.058 | - |
acetyl-CoA | at 37°C | Homo sapiens | |
0.12 | - |
ATP | at 37°C | Homo sapiens | |
0.147 | - |
ATP | at 37°C | Rattus norvegicus | |
0.147 | - |
ATP | at 37°C | Homo sapiens | |
3 | - |
HCO3- | at 37°C | Homo sapiens | |
5.1 | - |
HCO3- | at 37°C | Rattus norvegicus | |
12.8 | - |
HCO3- | at 37°C | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
250000 | - |
gel filtration | Rattus norvegicus |
250000 | - |
gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O00763 | - |
- |
Homo sapiens | Q13085 | - |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
c-Myc-5 monoclonal IgG column chromatography and Sephacryl S-300 gel filtration | Rattus norvegicus |
c-Myc-5 monoclonal IgG column chromatography and Sephacryl S-300 gel filtration | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
muscle | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + acetyl-CoA + HCO3- | - |
Rattus norvegicus | ADP + phosphate + malonyl-CoA | - |
? | |
ATP + acetyl-CoA + HCO3- | - |
Homo sapiens | ADP + phosphate + malonyl-CoA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ACC1 | - |
Homo sapiens |
ACC2 | - |
Rattus norvegicus |
ACC2 | - |
Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
10.1 | - |
acetyl-CoA | at 37°C | Homo sapiens | |
11.6 | - |
acetyl-CoA | at 37°C | Rattus norvegicus | |
11.8 | - |
acetyl-CoA | at 37°C | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Rattus norvegicus | |
ATP | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0008 | - |
palmitoyl-CoA | - |
Homo sapiens | |
0.009 | - |
malonyl-CoA | - |
Homo sapiens |