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Literature summary for 6.4.1.2 extracted from
- Increased fatty acid production in potato by engineering of acetyl-CoA carboxylase (2004), Planta, 219, 389-396.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| overexpression of isozyme ACC1 in the amyloplast of Solanum tuberosum tubers using the Agrobacterium transfection system | Arabidopsis thaliana |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | construction of transgenic potato plants by overexpression of the Arabidopsis thaliana isozyme ACC1 in the amyloplast of Solanum tuberosum tubers leads to an increased fatty acid synthesis and a 5fold increased amount of triacylglycerol in the tubers | Arabidopsis thaliana |
| additional information | construction of transgenic potato plants by overexpression of the Arabidopsis thaliana isozyme ACC1 in the amyloplast of tubers leads to an increased fatty acid synthesis and a 5fold increased amount of triacylglycerol in the tubers, up to 10fold increased enzyme activity in transgenic plants | Solanum tuberosum |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Solanum tuberosum |  |
| Mg2+ | - |
Arabidopsis thaliana | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 200000 | - |
x * 200000, SDS-PAGE | Solanum tuberosum |
| 200000 | - |
x * 200000, recombinant enzyme, SDS-PAGE | Arabidopsis thaliana |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + acetyl-CoA + HCO3- | Arabidopsis thaliana | - |
ADP + malonyl-CoA + phosphate | - |
? | |
| ATP + acetyl-CoA + HCO3- | Solanum tuberosum | the enzyme activity is limiting for lipid synthesis in tubers, biosynthetic pathway and regulatory aspects, overview | ADP + malonyl-CoA + phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | - |
isozyme ACC1 | - |
| Solanum tuberosum | - |
cv. Desiree | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| seed | - |
Arabidopsis thaliana | - |
| tuber | - |
Solanum tuberosum | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.000009 | - |
wild-type tuber | Solanum tuberosum |
| 0.000086 | 0.000096 | transgenic tubers highly overexpressing the Arabidopsis thaliana enzyme | Solanum tuberosum |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + acetyl-CoA + HCO3- | - |
Solanum tuberosum | ADP + malonyl-CoA + phosphate | - |
? | |
| ATP + acetyl-CoA + HCO3- | - |
Arabidopsis thaliana | ADP + malonyl-CoA + phosphate | - |
? | |
| ATP + acetyl-CoA + HCO3- | the enzyme activity is limiting for lipid synthesis in tubers, biosynthetic pathway and regulatory aspects, overview | Solanum tuberosum | ADP + malonyl-CoA + phosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 200000, SDS-PAGE | Solanum tuberosum |
| ? | x * 200000, recombinant enzyme, SDS-PAGE | Arabidopsis thaliana |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ACC1 | - |
Solanum tuberosum |
| ACC1 | - |
Arabidopsis thaliana |
| ACCase | - |
Solanum tuberosum |
| ACCase | - |
Arabidopsis thaliana |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Solanum tuberosum |
| 30 | - |
assay at | Arabidopsis thaliana |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.2 | - |
assay at | Solanum tuberosum |
| 8.2 | - |
assay at | Arabidopsis thaliana |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Solanum tuberosum | |
| ATP | - |
Arabidopsis thaliana | |
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Release 2023.1 (January 2023)
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