Cloned (Comment) | Organism |
---|---|
DNA and amino acid sequence determination and analysis of the plastidic isozyme | Nicotiana tabacum |
DNA and amino acid sequence determination and analysis of the plastidic isozyme, genes accA-accD encode the 4 subunits, expression of the carboxyltransferase subunit | Pisum sativum |
gene dedB, i.e. accD, encoding the beta subunit of the carboxyltransferase | Escherichia coli |
genes acc1 and acc2, Oryza sativa lacks the accD gene which encodes for the biotin carboxyl carrier protein in plants other than the Gramineae | Oryza sativa |
genes acc1 and acc2, Triticum aestivum lacks the accD gene which encodes for the biotin carboxyl carrier protein in plants other than the Gramineae | Triticum aestivum |
subunit BCCP is encoded by 2 genes, while the other 3 subunits are single gene-encoded | Arabidopsis thaliana |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
chloroplast | plastidic isozyme, associated with the chloroplast envelope | Triticum aestivum | 9507 | - |
chloroplast envelope | plastidic isozyme, associated with the chloroplast envelope | Pisum sativum | 9941 | - |
chloroplast envelope | plastidic isozyme, associated with the chloroplast envelope | Nicotiana tabacum | 9941 | - |
chloroplast envelope | plastidic isozyme, associated with the chloroplast envelope | Arabidopsis thaliana | 9941 | - |
chloroplast envelope | plastidic isozyme, associated with the chloroplast envelope | Brassica napus | 9941 | - |
chloroplast envelope | plastidic isozyme, associated with the chloroplast envelope | Oryza sativa | 9941 | - |
cytosol | cytosolic isozyme | Triticum aestivum | 5829 | - |
cytosol | cytosolic isozyme | Pisum sativum | 5829 | - |
cytosol | cytosolic isozyme | Nicotiana tabacum | 5829 | - |
cytosol | cytosolic isozyme | Arabidopsis thaliana | 5829 | - |
cytosol | cytosolic isozyme | Brassica napus | 5829 | - |
cytosol | cytosolic isozyme | Oryza sativa | 5829 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Escherichia coli | |
Mg2+ | - |
Triticum aestivum | |
Mg2+ | - |
Pisum sativum | |
Mg2+ | - |
Nicotiana tabacum | |
Mg2+ | - |
Arabidopsis thaliana | |
Mg2+ | - |
Brassica napus | |
Mg2+ | - |
Oryza sativa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
490000 | - |
native and recombinant carboxyltransferase subunit, gel filtration | Pisum sativum |
500000 | - |
about, cytosolic enzyme form, gel filtration | Pisum sativum |
650000 | 700000 | about, plastidic enzyme form, gel filtration | Pisum sativum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + acetyl-CoA + HCO3- | Escherichia coli | first committed step of fatty acid synthesis | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | Triticum aestivum | first committed step of fatty acid synthesis, physiological role, regulation by RNA editing, post-transcriptional, and by stromal pH, photosynthetic redox cascade, and Mg2+ concentration, overview | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | Oryza sativa | first committed step of fatty acid synthesis, physiological role, regulation by RNA editing, post-transcriptional, and by stromal pH, photosynthetic redox cascade, and Mg2+ concentration, overview | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | Pisum sativum | first committed step of fatty acid synthesis, physiological roles of the isozymes, regulation by RNA editing, post-transcriptional, and by pH, redox, and Mg2+ concentration, overview | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | Nicotiana tabacum | first committed step of fatty acid synthesis, physiological roles of the isozymes, regulation by RNA editing, post-transcriptional, and by stromal pH, photosynthetic redox cascade, and Mg2+ concentration, overview | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | Arabidopsis thaliana | first committed step of fatty acid synthesis, physiological roles of the isozymes, regulation by RNA editing, post-transcriptional, and by stromal pH, photosynthetic redox cascade, and Mg2+ concentration, overview | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | Brassica napus | first committed step of fatty acid synthesis, physiological roles of the isozymes, regulation by RNA editing, post-transcriptional, and by stromal pH, photosynthetic redox cascade, and Mg2+ concentration, overview | ADP + malonyl-CoA + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
- |
- |
Brassica napus | - |
- |
- |
Escherichia coli | - |
- |
- |
Nicotiana tabacum | - |
- |
- |
Oryza sativa | - |
- |
- |
Pisum sativum | - |
- |
- |
Triticum aestivum | - |
- |
- |
Purification (Comment) | Organism |
---|---|
beta subunit of the carboxyltransferase | Escherichia coli |
partial purification of the carboxyltransferase subunit | Pisum sativum |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
seedling | - |
Pisum sativum | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + acetyl-CoA + HCO3- | first committed step of fatty acid synthesis | Escherichia coli | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | first committed step of fatty acid synthesis, physiological role, regulation by RNA editing, post-transcriptional, and by stromal pH, photosynthetic redox cascade, and Mg2+ concentration, overview | Triticum aestivum | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | first committed step of fatty acid synthesis, physiological role, regulation by RNA editing, post-transcriptional, and by stromal pH, photosynthetic redox cascade, and Mg2+ concentration, overview | Oryza sativa | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | first committed step of fatty acid synthesis, physiological roles of the isozymes, regulation by RNA editing, post-transcriptional, and by pH, redox, and Mg2+ concentration, overview | Pisum sativum | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | first committed step of fatty acid synthesis, physiological roles of the isozymes, regulation by RNA editing, post-transcriptional, and by stromal pH, photosynthetic redox cascade, and Mg2+ concentration, overview | Nicotiana tabacum | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | first committed step of fatty acid synthesis, physiological roles of the isozymes, regulation by RNA editing, post-transcriptional, and by stromal pH, photosynthetic redox cascade, and Mg2+ concentration, overview | Arabidopsis thaliana | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | first committed step of fatty acid synthesis, physiological roles of the isozymes, regulation by RNA editing, post-transcriptional, and by stromal pH, photosynthetic redox cascade, and Mg2+ concentration, overview | Brassica napus | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | the enzyme exhibits malonyl-CoA carboxylase and biotin carboxylase activity | Escherichia coli | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | the enzyme exhibits malonyl-CoA carboxylase and biotin carboxylase activity | Triticum aestivum | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | the enzyme exhibits malonyl-CoA carboxylase and biotin carboxylase activity | Pisum sativum | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | the enzyme exhibits malonyl-CoA carboxylase and biotin carboxylase activity | Nicotiana tabacum | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | the enzyme exhibits malonyl-CoA carboxylase and biotin carboxylase activity | Arabidopsis thaliana | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | the enzyme exhibits malonyl-CoA carboxylase and biotin carboxylase activity | Brassica napus | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | the enzyme exhibits malonyl-CoA carboxylase and biotin carboxylase activity | Oryza sativa | ADP + malonyl-CoA + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 210000-250000, homomeric cytosolic enzyme form, SDS-PAGE | Pisum sativum |
dimer | homomeric cytosolic and plastidic enzyme form | Triticum aestivum |
dimer | homomeric cytosolic and plastidic enzyme form | Oryza sativa |
dimer | homomeric cytosolic enzyme form | Nicotiana tabacum |
dimer | homomeric cytosolic enzyme form | Arabidopsis thaliana |
dimer | homomeric cytosolic enzyme form | Brassica napus |
More | plants possess a homomeric single polypeptide enzyme form in the cytosol, and a heterotetrameric plastidic enzyme form | Pisum sativum |
More | plants possess a homomeric single polypeptide enzyme form in the cytosol, and a heterotetrameric plastidic enzyme form | Nicotiana tabacum |
More | plants possess a homomeric single polypeptide enzyme form in the cytosol, and a heterotetrameric plastidic enzyme form | Arabidopsis thaliana |
More | plants possess a homomeric single polypeptide enzyme form in the cytosol, and a heterotetrameric plastidic enzyme form | Brassica napus |
tetramer | heterotetrameric plastidic enzyme form, the heterotetramer is composed of the subunits biotin carboxyl carrier protein BCCP of 21 kDa, biotin carboxylase BC of 53 kDa, and alpha and beta subunits of the carboxyltransferase CT of 91 kDa and 67 kDa | Pisum sativum |
tetramer | heterotetrameric plastidic enzyme form, the heterotetramer is composed of the subunits biotin carboxyl carrier protein BCCP, biotin carboxylase BC, and alpha and beta subunits of the carboxyltransferase CT | Nicotiana tabacum |
tetramer | heterotetrameric plastidic enzyme form, the heterotetramer is composed of the subunits biotin carboxyl carrier protein BCCP, biotin carboxylase BC, and alpha and beta subunits of the carboxyltransferase CT | Arabidopsis thaliana |
tetramer | heterotetrameric plastidic enzyme form, the heterotetramer is composed of the subunits biotin carboxyl carrier protein BCCP, biotin carboxylase BC, and alpha and beta subunits of the carboxyltransferase CT | Brassica napus |
tetramer | the heterotetramer is composed of the subunits biotin carboxyl carrier protein BCCP of 17 kDa, biotin carboxylase BC of 49 kDa, and alpha and beta subunits of the carboxyltransferase CT of 35 kDa and 33 kDa | Escherichia coli |
Synonyms | Comment | Organism |
---|---|---|
ACCase | - |
Escherichia coli |
ACCase | - |
Triticum aestivum |
ACCase | - |
Pisum sativum |
ACCase | - |
Nicotiana tabacum |
ACCase | - |
Arabidopsis thaliana |
ACCase | - |
Brassica napus |
ACCase | - |
Oryza sativa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Escherichia coli | |
ATP | - |
Triticum aestivum | |
ATP | - |
Pisum sativum | |
ATP | - |
Nicotiana tabacum | |
ATP | - |
Arabidopsis thaliana | |
ATP | - |
Brassica napus | |
ATP | - |
Oryza sativa | |
biotin | - |
Escherichia coli | |
biotin | - |
Triticum aestivum | |
biotin | - |
Pisum sativum | |
biotin | - |
Nicotiana tabacum | |
biotin | - |
Arabidopsis thaliana | |
biotin | - |
Brassica napus | |
biotin | - |
Oryza sativa |