Literature summary for 6.4.1.2 extracted from

Travers, M.T.; Vallance, A.J.; Clegg, R.A.; Thomson, R.; Price, N.T.; Barber, M.C.
Characterisation of an N-terminal variant of acetyl-CoA carboxylase-alpha: expression in human tissues and evolutionary aspects (2003), Biochim. Biophys. Acta, 1634, 97-106.

Search for more literature for 6.4.1.2

Cloned(Commentary)

Cloned (Comment)	Organism
expressed as His-tag fusion preteon in Escherichia coli Rosetta DE3	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
250000	-	SDS-PAGE	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + acetyl-CoA + HCO3-	Homo sapiens	key enzyme of fatty acid biosynthesis	ADP + phosphate + malonyl-CoA	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q13085	-	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant protein from Escherichia coli using His-tag	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + acetyl-CoA + HCO3-	-	Homo sapiens	ADP + phosphate + malonyl-CoA	-	?
ATP + acetyl-CoA + HCO3-	key enzyme of fatty acid biosynthesis	Homo sapiens	ADP + phosphate + malonyl-CoA	-	?

Cofactor

Cofactor	Comment	Organism	Structure
biotin	enzyme-bound	Homo sapiens

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Release 2023.1 (January 2023)