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Literature summary for 6.4.1.2 extracted from
- Formation of malonyl coenzyme A in rat heart. Identification and purification of an isozyme of A carboxylase from rat heart (1989), J. Biol. Chem., 264, 17631-17634.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| citrate | weak activity in absence of citrate | Rattus norvegicus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Avidin | - |
Rattus norvegicus | |
| malonyl-CoA | - |
Rattus norvegicus | |
| palmitoyl-CoA | - |
Rattus norvegicus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 265000 | - |
x * 265000, liver, SDS-PAGE | Rattus norvegicus |
| 280000 | - |
x * 280000, heart, SDS-PAGE | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| heart | - |
Rattus norvegicus | - |
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + acetyl-CoA + HCO3- | - |
Rattus norvegicus | ADP + phosphate + malonyl-CoA | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 280000, heart, SDS-PAGE | Rattus norvegicus |
| ? | x * 265000, liver, SDS-PAGE | Rattus norvegicus |
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