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BRENDA support

Literature summary for 6.4.1.1 extracted from

  • Islam, M.N.; Sueda, S.; Kondo, H.
    Construction of new forms of pyruvate carboxylase to assess the allosteric regulation by acetyl-CoA (2005), PROTEIN ENG. DES. SEL., 18, 71-78.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
acetyl-CoA
-
Geobacillus thermodenitrificans

Cloned(Commentary)

Cloned (Comment) Organism
expression of the subunits biotin carboxylase BC and carboxyl transferase CT (PC-(BC+CT)) and biotin carboxyl carrier protein BCCP (PC-(BCCP)) in Escherichia coli JM109 Geobacillus thermodenitrificans

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.039
-
pyruvate
-
Geobacillus thermodenitrificans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + pyruvate + HCO3- Geobacillus thermodenitrificans
-
ADP + oxaloacetate + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Geobacillus thermodenitrificans
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Geobacillus thermodenitrificans

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + pyruvate + HCO3-
-
Geobacillus thermodenitrificans ADP + oxaloacetate + phosphate
-
?

Synonyms

Synonyms Comment Organism
PC
-
Geobacillus thermodenitrificans