Activating Compound | Comment | Organism | Structure |
---|---|---|---|
N-acetyl-L-glutamate | - |
Galeus melastomus | |
N-acetyl-L-glutamate | activation of CPS III, not CPS II | Hippoglossus hippoglossus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | not: UTP | Galeus melastomus | |
UTP | when L-glutamine is the substrate: 94% inhibition of enzyme activity peak 1: CPS II, 6% inhibition of enzyme activity peak 2: CPS III, when NH4Cl is the substrate: 100% inhibition of enzyme activity peak 1: CPS II, 46% inhibition of enzyme activity peak 2: CPS III | Hippoglossus hippoglossus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
160000 | 170000 | gel filtration, CPS III | Hippoglossus hippoglossus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ATP + L-Gln + HCO3- | Hippoglossus hippoglossus | enzyme catalyses the first step of urea cycle in fish | 2 ADP + phosphate + L-Glu + carbamoyl phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Galeus melastomus | - |
Blackmous catshark | - |
Hippoglossus hippoglossus | - |
atlantic halibut, yolk-sac larvae and adult, two enzymes: CPS II and CPS III | - |
Source Tissue | Comment | Organism | Textmining |
---|
Storage Stability | Organism |
---|---|
-80°C, stable, 6 months | Hippoglossus hippoglossus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ATP + L-Gln + HCO3- | - |
Hippoglossus hippoglossus | 2 ADP + phosphate + L-Glu + carbamoyl phosphate | - |
? | |
2 ATP + L-Gln + HCO3- | - |
Galeus melastomus | 2 ADP + phosphate + L-Glu + carbamoyl phosphate | - |
? | |
2 ATP + L-Gln + HCO3- | enzyme catalyses the first step of urea cycle in fish | Hippoglossus hippoglossus | 2 ADP + phosphate + L-Glu + carbamoyl phosphate | - |
? | |
2 ATP + NH4+ + HCO3- | CPS III shows low activity in comparison to L-glutamine | Hippoglossus hippoglossus | 2 ADP + phosphate + carbamoyl phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
carbamoyl phosphate synthetase III | - |
Hippoglossus hippoglossus |
carbamoyl phosphate synthetase III | - |
Galeus melastomus |
CPS III | - |
Hippoglossus hippoglossus |
CPS III | - |
Galeus melastomus |