Application | Comment | Organism |
---|---|---|
agriculture | transgenic Arabidopsis thaliana plants that overexpress CaAS1 exhibit enhanced resistance to Pseudomonas syringae pv. tomato DC3000 and Hyaloperonospora arabidopsidis. Increased CaAS1 expression influences early defense responses in diseased leaves, including increased electrolyte leakage, reactive oxygen species and nitric oxide burst. In CaAS1-silenced pepper and/or CaAS1-overexpressing Arabidopsis, CaAS1-dependent changes in asparagine levels correlate with increased susceptibility or defense responses to microbial pathogens, respectively | Capsicum annuum |
Cloned (Comment) | Organism |
---|---|
gene CaAS1, enzyme overexpression in transgenic Arabidopsis thaliana plants leads to enhanced resistance of the plants to Pseudomonas syringae pv. tomato DC3000 and Hyaloperonospora arabidopsidis, phenotypes, overview | Capsicum annuum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-aspartate + L-glutamine + H2O | Capsicum annuum | - |
AMP + diphosphate + L-asparagine + L-glutamate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Capsicum annuum | - |
- |
- |
Capsicum annuum | - |
gene CaAS1 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leaf | - |
Capsicum annuum | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-aspartate + L-glutamine + H2O | - |
Capsicum annuum | AMP + diphosphate + L-asparagine + L-glutamate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AS1 | - |
Capsicum annuum |
asparagine synthetase 1 | - |
Capsicum annuum |
CaAS1 | - |
Capsicum annuum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Capsicum annuum |
Organism | Comment | Expression |
---|---|---|
Capsicum annuum | infection with Xanthomonas campestris pv. vesicatoria induces early and strong CaAS1 expression in leaves. Significant induction of CaAS1 expression occurs in pepper leaves following treatment with salicylic acid, methyl jasmonate or wounding | up |
Capsicum annuum | infection with Xanthomonas campestris pv. vesicatoria induces early and strong CaAS1 expression in pepper leaves | up |
General Information | Comment | Organism |
---|---|---|
evolution | CaAS1 and its related plant proteins all contain an AsnB domain and an ASN synthetase domain | Capsicum annuum |
malfunction | silencing of CaAS1 gene results in enhanced susceptibility to Xanthomonas campestris pv. vesicatoria infection, phenotypes, overview | Capsicum annuum |
additional information | transgenic Arabidopsis thaliana plants that overexpress CaAS1 exhibit enhanced resistance to Pseudomonas syringae pv. tomato DC3000 and Hyaloperonospora arabidopsidis | Capsicum annuum |
physiological function | silencing of the gene encoding AS1 results in enhanced susceptibility to Xanthomonas campestris pv. vesicatoria infection. Transgenic Arabidopsis thaliana plants that overexpress CaAS1 exhibit enhanced resistance to Pseudomonas syringae pv. tomato DC3000 and Hyaloperonospora arabidopsidis. Increased CaAS1 expression influences early defense responses in diseased leaves, including increased electrolyte leakage, reactive oxygen species and nitric oxide burst. In CaAS1-silenced pepper and/or CaAS1-overexpressing Arabidopsis, CaAS1-dependent changes in asparagine levels correlate with increased susceptibility or defense responses to microbial pathogens, respectively | Capsicum annuum |
physiological function | asparagine synthetase 1 is essential for plant defense to microbial pathogens. Increased CaAS1 expression influences early defense responses in diseased leaves, including increased electrolyte leakage, reactive oxygen species and nitric oxide bursts. In plants, increased conversion of aspartate to asparagine appears to be associated with enhanced resistance to bacterial and oomycete pathogens, phenotypes, overview | Capsicum annuum |