Cloned (Comment) | Organism |
---|---|
expression of several mutant enymes in Saccharomyces cerevisiae | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
C1A | altering Cys-1 to either Ala or Ser eliminated the Gln-dependent activity, while only minimally affecting the kinetic properties of the NH4+-dependent reaction | Homo sapiens |
C1S | altering Cys-1 to either Ala or Ser eliminated the Gln-dependent activity, while only minimally affecting the kinetic properties of the NH4+-dependent reaction | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Gln | 0.4-2.0 mM, inhibits the ammonia-dependent production of Asn | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-Asp + L-Gln | - |
Homo sapiens | AMP + diphosphate + Asn + Glu | - |
? | |
ATP + L-Asp + NH3 | - |
Homo sapiens | AMP + diphosphate + Asn | - |
? |