Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 6.3.5.3 extracted from

  • Mangold, C.A.; Yao, P.J.; Du, M.; Freeman, W.M.; Benkovic, S.J.; Szpara, M.L.
    Expression of the purine biosynthetic enzyme phosphoribosyl formylglycinamidine synthase (FGAMS) in neurons (2018), J. Neurochem., 144, 723-735 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.3.5.3

Application

Application Comment Organism
medicine in fibroblasts infected with the human pathogen herpes simplex virus 1, FGAMS immunolabeling shifts from a diffuse cytoplasmic location to a mainly perinuclear localization by 12 hours post infection. In infected rat neurons, FGAMS localization shows no discernable changes. There are no changes in total FGAMS protein levels in either cell type Rattus norvegicus
medicine in fibroblasts infected with the human pathogen herpes simplex virus 1, FGAMS immunolabeling shifts from a diffuse cytoplasmic location to a mainly perinuclear localization by 12 hours post infection. In infected rat neurons, FGAMS localization shows no discernable changes. There are no changes in total FGAMS protein levels in either cell type Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Rattus norvegicus 5737
-
cytoplasm
-
 Homo sapiens 5737
-

Organism

Organism UniProt Comment Textmining
Homo sapiens O15067
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
neuron
-
 Rattus norvegicus
-
SH-SY5Y cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
FGAMS
-
 Rattus norvegicus
FGAMS
-
 Homo sapiens
PFAS
-
 Rattus norvegicus
PFAS
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function in fibroblasts infected with the human pathogen herpes simplex virus 1, FGAMS immunolabeling shifts from a diffuse cytoplasmic location to a mainly perinuclear localization by 12 hours post infection. In infected rat neurons, FGAMS localization shows no discernable changes. There are no changes in total FGAMS protein levels in either cell type Rattus norvegicus
physiological function in fibroblasts infected with the human pathogen herpes simplex virus 1, FGAMS immunolabeling shifts from a diffuse cytoplasmic location to a mainly perinuclear localization by 12 hours post infection. In infected rat neurons, FGAMS localization shows no discernable changes. There are no changes in total FGAMS protein levels in either cell type Homo sapiens