Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli DH5alpha cells | Escherichia coli |
Protein Variants | Comment | Organism |
---|---|---|
37W | the mutant shows severely reduced specific activity compared to the wild type enzyme | Escherichia coli |
W37A | the mutant shows slightly reduced specific activity compared to the wild type enzyme | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
XMP | substrate inhibition above 0.2 mM | Escherichia coli |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + XMP + L-glutamine + H2O | Escherichia coli | - |
AMP + diphosphate + GMP + L-glutamate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + XMP + L-glutamine + H2O | - |
Escherichia coli | AMP + diphosphate + GMP + L-glutamate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GMP synthetase | - |
Escherichia coli |
GMPS | - |
Escherichia coli |
GuaA | - |
Escherichia coli |
Guanosine 5'-monophosphate synthetase | - |
Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Escherichia coli |