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Literature summary for 6.3.4.5 extracted from

  • Saheki, T.; Sase, M.; Nakano, K.; Azuma, F.; Katsunuma, T.
    Some properties of argininosuccinate synthetase purified from human liver and a comparison with the rat liver enzyme (1983), J. Biochem., 93, 1531-1537.
    View publication on PubMed
Search for more literature for 6.3.4.5

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.019
-
 Asp reaction with 5 mM citrulline Homo sapiens
0.024
-
 citrulline reaction with 5 mM Asp Homo sapiens
0.042
-
 citrulline reaction with 0.5 mM Asp Homo sapiens
0.077
-
 ATP citrulline Homo sapiens
0.083
-
 Asp reaction with 0.5 mM citrulline Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
45000
-
 4 * 45000, SDS-PAGE Homo sapiens
185000
-
 gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.3
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + citrulline + aspartate
-
 Homo sapiens AMP + diphosphate + 2-(Nomega-L-arginino)succinate
-
 ?
ATP + L-citrulline + L-Asp
-
 Homo sapiens AMP + diphosphate + L-argininosuccinate
-
 ?
ATP + L-citrulline + L-Asp
-
 Rattus norvegicus AMP + diphosphate + L-argininosuccinate
-
 ?

Subunits

Subunits Comment Organism
tetramer
-
 Rattus norvegicus
tetramer 4 * 45000, SDS-PAGE Homo sapiens