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Literature summary for 6.3.4.5 extracted from

  • Kimball, M.E.; Jacoby, L.B.
    Purification and properties of argininosuccinate synthetase from normal and canavanine-resistant human lymphoblasts (1980), Biochemistry, 19, 705-709.
    View publication on PubMed
Search for more literature for 6.3.4.5

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information ATP: biphasic double-reciprocal plot Homo sapiens
0.061
-
 citrulline MGL8B2 enzyme Homo sapiens
0.078
-
 Asp MGL8B2 enzyme and MGL8D1 enzyme Homo sapiens
0.089
-
 citrulline MGL8D1 enzyme Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
45000
-
 4 * 45000, SDS-PAGE Homo sapiens
180000
-
 gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
lymphoblast parental cell line MGL8B2 and canavanine-resistant cell line MGL8D1 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.95
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + citrulline + aspartate
-
 Homo sapiens AMP + diphosphate + 2-(Nomega-L-arginino)succinate
-
 ?
ATP + L-citrulline + L-Asp
-
 Homo sapiens AMP + diphosphate + L-argininosuccinate
-
 ?

Subunits

Subunits Comment Organism
tetramer 4 * 45000, SDS-PAGE Homo sapiens