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Literature summary for 6.3.4.4 extracted from

  • Porter, D.J.T.; Rudie, N.G.; Bright, H.J.
    Nitro analogs of substrates for adenylosuccinate synthetase and adenylosuccinate lyase (1983), Arch. Biochem. Biophys., 225, 157-163.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
4-Oxo-2-aminopentanoic acid i.e. 2-oxonorvaline, poor Azotobacter vinelandii
cyanoalanine poor Azotobacter vinelandii
cysteine poor Azotobacter vinelandii
cysteine sulfonate poor Azotobacter vinelandii
homocysteine poor Azotobacter vinelandii
methionine sulfone poor Azotobacter vinelandii
N-Hydroxyaspartate poor Azotobacter vinelandii
N-methylaspartate poor Azotobacter vinelandii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + IMP + L-Asp Azotobacter vinelandii penultimate step in pathway of AMP biosynthesis ?
-
?

Organism

Organism UniProt Comment Textmining
Azotobacter vinelandii
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + IMP + Ala-3-nitronate
-
Azotobacter vinelandii GDP + phosphate + N6-(L-1-carboxy-2-nitroethyl)AMP
-
?
GTP + IMP + cysteine sulfinate
-
Azotobacter vinelandii ?
-
?
GTP + IMP + L-Asp
-
Azotobacter vinelandii GDP + phosphate + adenylosuccinate
-
?
GTP + IMP + L-Asp penultimate step in pathway of AMP biosynthesis Azotobacter vinelandii ?
-
?