Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 6.3.4.21 extracted from

  • Duarte-Pereira, S.; Pereira-Castro, I.; Silva, S.S.; Correia, M.G.; Neto, C.; da Costa, L.T.; Amorim, A.; Silva, R.M.
    Extensive regulation of nicotinate phosphoribosyltransferase (NAPRT) expression in human tissues and tumors (2016), Oncotarget, 7, 1973-1983 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell weak expression Homo sapiens
-
C-643 cell weak expression Homo sapiens
-
Caki-2 cell weak expression Homo sapiens
-
HEK-293 cell weak expression Homo sapiens
-
additional information gene is ubiquitously expressed at the mRNA level in all normal human tissues tested. No expression MKN-28 cell Homo sapiens
-

Expression

Organism Comment Expression
Homo sapiens presence of more than one NAPRT transcript in most tissues, all with identical 3' end sequence. Some NAPRT transcripts appear to be tissuespecific. Brain shows the highest number of alternative transcripts. Several modulators of the NAPRT gene expression are involved, i.e. mutations in transcription factor binding sites, promoter methylation and alternative splicing additional information