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Literature summary for 6.3.4.2 extracted from

  • Verschuur, A.C.; van Gennip, A.H.; Muller, E.J.; Voute, P.A.; Vreken, P.; Van Kuilenburg, A.B.
    Cytidine triphosphate synthase activity and mRNA expression in normal human blood cells (1999), Biol. Chem., 380, 41-46.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme is one of the key enzymes in pyrimidine nucleotide anabolic pathways. The activity of this enzyme is elevated in various malignancies including acute lymphocytic leukemia ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
 Homo sapiens
-
granulocyte
-
 Homo sapiens
-
lymphocyte
-
 Homo sapiens
-
monocyte
-
 Homo sapiens
-
thrombocyte highest activity is found in thombocytes, followed by monocytes, lymphocytes, granulocytes and erythrocytes Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + UTP + NH4+
-
 Homo sapiens ADP + phosphate + CTP
-
 ?
additional information the enzyme is one of the key enzymes in pyrimidine nucleotide anabolic pathways. The activity of this enzyme is elevated in various malignancies including acute lymphocytic leukemia Homo sapiens ?
-
 ?