Literature summary for 6.3.4.16 extracted from

Nohara, K.; Shin, Y.; Park, N.; Jeong, K.; He, B.; Koike, N.; Yoo, S.; Chen, Z.
Ammonia-lowering activities and carbamoyl phosphate synthetase 1 (Cps1) induction mechanism of a natural flavonoid (2015), Nutr. Metab., 12, 23 .

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Mus musculus	5739	-

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	Q8C196	-	-

Synonyms

Synonyms	Comment	Organism
CPS1	-	Mus musculus

Expression

Organism	Comment	Expression
Mus musculus	nobiletin is able to lower serum ammonia levels in mice fed with regular chow (RC), high-fat (HFD) or high-protein diet. NOB rescues CPS1 protein levels under the HFD condition via induction of the transcription factors C/EBPalpha and C/EBPbeta. HPD markedly increases CPS1 levels relative to RC. A functional circadian clock, is required for nobiletin induction of CPS1 under the HFD condition	up

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Release 2023.1 (January 2023)