Protein Variants | Comment | Organism |
---|---|---|
E23R | the mutant protein has a kcat value about 30% that of the wild type enzyme | Escherichia coli |
F363A | the mutant has approximately 84% of the wild type activity | Escherichia coli |
R19E | the mutant has about half the activity of the wild type protein | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + biotin-carboxyl-carrier protein + HCO3- | Escherichia coli | - |
ADP + phosphate + carboxybiotin-carboxyl-carrier protein | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
substr. MG1655 | - |
Purification (Comment) | Organism |
---|---|
partial purification | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + biotin-carboxyl-carrier protein + HCO3- | - |
Escherichia coli | ADP + phosphate + carboxybiotin-carboxyl-carrier protein | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | - |
Escherichia coli |
Synonyms | Comment | Organism |
---|---|---|
AccC | - |
Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Escherichia coli |
General Information | Comment | Organism |
---|---|---|
physiological function | dimerization of the biotin carboxylase subunit is required for acetyl coenzyme A carboxylase activity in vivo | Escherichia coli |