Literature summary for 6.3.4.14 extracted from

Guchhait, R.B.; Polakis, S.E.; Hollis, D.; Fenselau, C.; Lane, M.D.
Acetyl coenzyme A carboxylase system of Escherichia coli. Site of carboxylation of biotin and enzymatic reactivity of 1'-N-(ureido)-carboxybiotin derivatives (1974), J. Biol. Chem., 24 9, 6646-6656.

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Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + 1'-N-carboxy-D-biotin + HCO3-	the 1'-ureido-N position of biotin is the enzymatic site of carboxylation	Escherichia coli	ADP + phosphate + ?	-	?
ATP + biotin-carboxyl-carrier protein + HCO3-	-	Escherichia coli	ADP + phosphate + carboxybiotin-carboxyl-carrier protein	-	?

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Release 2023.1 (January 2023)