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Literature summary for 6.3.4.10 extracted from

  • Reyes-Carmona, S.; Valadez-Graham, V.; Aguilar-Fuentes, J.; Zurita, M.; Leon-Del-Rio, A.
    Trafficking and chromatin dynamics of holocarboxylase synthetase during development of Drosophila melanogaster (2011), Mol. Genet. Metab., 103, 240-248.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Drosophila melanogaster

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus HCS migrates to the nucleus at the gastrulation stage. In polytene chromosomes, it is associated to heterochromatin bands where it co-localizes with histone 3 trimethylated at lysine 9 but not with the euchromatin mark histone 3 acetylated at lysine 9. HCS associates with the hsp70 promoter. On heat-shock activation of the hsp70 promoter, HCS is displaced and the promoter region becomes enriched with the TFIIH subunits XPD and XPB and elongating RNA pol I Drosophila melanogaster 5634
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Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
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-
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Source Tissue

Source Tissue Comment Organism Textmining
embryo
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 Drosophila melanogaster
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salivary gland
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 Drosophila melanogaster
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General Information

General Information Comment Organism
physiological function HCS migrates to the nucleus at the gastrulation stage. In polytene chromosomes, it is associated to heterochromatin bands where it co-localizes with histone 3 trimethylated at lysine 9 but not with the euchromatin mark histone 3 acetylated at lysine 9. HCS associates with the hsp70 promoter. On heat-shock activation of the hsp70 promoter, HCS is displaced and the promoter region becomes enriched with the TFIIH subunits XPD and XPB and elongating RNA pol I Drosophila melanogaster