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Literature summary for 6.3.3.2 extracted from

  • Goyer, A.; Collakova, E.; Diaz de la Garza, R.; Quinlivan, E.P.; Williamson, J.; Gregory, J.F., 3rd; Shachar-Hill, Y.; Hanson, A.D.
    5-Formyltetrahydrofolate is an inhibitory but well tolerated metabolite in Arabidopsis leaves (2005), J. Biol. Chem., 280, 26137-26142.
    View publication on PubMed
Search for more literature for 6.3.3.2

Cloned(Commentary)

Cloned (Comment) Organism
insertional mutant DNA sequence determination and analysis Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information insertional mutation of the gene encoding the enzyme, At5g13050 or 28D07, reduces the growth rate of the mutant plants by 20% and delayes flowering by 1 week, and leads to accumulation of 5-formyltetrahydrofolate and glycine in leaves under photorespiratory conditions, effect of 5-formyltetrahydrofolate feeding, overview Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Arabidopsis thaliana 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 5-formyltetrahydrofolate Arabidopsis thaliana recycling reaction ADP + 5,10-methenyltetrahydrofolate + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
 ecotype Columbia
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 5-formyltetrahydrofolate
-
 Arabidopsis thaliana ADP + 5,10-methenyltetrahydrofolate + phosphate
-
 ?
ATP + 5-formyltetrahydrofolate recycling reaction Arabidopsis thaliana ADP + 5,10-methenyltetrahydrofolate + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
5,10-Methenyltetrahydrofolate synthetase
-
 Arabidopsis thaliana
5-CHO-THF cycloligase
-
 Arabidopsis thaliana
5-FCL
-
 Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Arabidopsis thaliana