KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0051 | - |
5-formyltetrahydrofolate | - |
Rattus norvegicus | |
0.05 | - |
ATP | - |
Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 5-formyltetrahydrofolate | Homo sapiens | - |
? | - |
? | |
ATP + 5-formyltetrahydrofolate | Rattus norvegicus | key enzymatic reaction in the pathway by which 5-formyltetrahydrofolate enters the folate coenzyme pool | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cricetulus griseus | - |
- |
- |
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bone marrow | - |
Rattus norvegicus | - |
brain | low activity | Rattus norvegicus | - |
CEM cell | T-lymphoblast cell line CEM and its methotrexate resistant subline, colon tumor cell line | Homo sapiens | - |
CHO cell | CHO, ovary cell line and its methotrexate resistant subline | Cricetulus griseus | - |
colon | - |
Rattus norvegicus | - |
colonic cancer cell line | - |
Cricetulus griseus | - |
colonic cancer cell line | T-lymphoblast cell line CEM and its methotrexate resistant subline, colon tumor cell line | Homo sapiens | - |
intestine | - |
Rattus norvegicus | - |
kidney | - |
Rattus norvegicus | - |
liver | - |
Homo sapiens | - |
liver | highest activity compared to other tissues | Rattus norvegicus | - |
lung | low activity | Rattus norvegicus | - |
muscle | low activity | Rattus norvegicus | - |
spleen | - |
Rattus norvegicus | - |
testis | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 5-formyltetrahydrofolate | - |
Cricetulus griseus | ADP + phosphate + 5,10-methylenetetrahydrofolate | - |
? | |
ATP + 5-formyltetrahydrofolate | - |
Homo sapiens | ADP + phosphate + 5,10-methylenetetrahydrofolate | - |
? | |
ATP + 5-formyltetrahydrofolate | - |
Rattus norvegicus | ADP + phosphate + 5,10-methylenetetrahydrofolate | - |
? | |
ATP + 5-formyltetrahydrofolate | - |
Homo sapiens | ? | - |
? | |
ATP + 5-formyltetrahydrofolate | key enzymatic reaction in the pathway by which 5-formyltetrahydrofolate enters the folate coenzyme pool | Rattus norvegicus | ? | - |
? |