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Literature summary for 6.3.2.6 extracted from

  • Hilton Patey, C.A.; Shaw, G.
    Purification and properties of an enzyme duet, phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthetase, involved in the biosynthesis of purine nucleotides de novo (1973), Biochem. J., 135, 543-545.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
PCMB
-
Gallus gallus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
52000
-
x * 52000, SDS-PAGE Gallus gallus
350000
-
gel filtration Gallus gallus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 1-(5'-phosphoribosyl)-5-amino-4-carboxyimidazole + L-Asp Gallus gallus one of the enzymes of the series involved in the biosynthesis of the purine nucleotides de novo ?
-
?

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
copurification of EC 4.1.1.21/EC 6.3.2.6 Gallus gallus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1-(5'-phosphoribosyl)-5-amino-4-carboxyimidazole + L-Asp
-
Gallus gallus ADP + phosphate + 1-(5'-phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
-
?
ATP + 1-(5'-phosphoribosyl)-5-amino-4-carboxyimidazole + L-Asp one of the enzymes of the series involved in the biosynthesis of the purine nucleotides de novo Gallus gallus ?
-
?

Subunits

Subunits Comment Organism
? x * 52000, SDS-PAGE Gallus gallus