Literature summary for 6.3.2.4 extracted from

Prevost, M.; Van Belle, D.; Tulkens, P.M.; Courvalin, P.; Van Bambeke, F.
Modeling of Enterococcus faecalis D-alanine:D-alanine ligase: structure-based study of the active site in the wild-type enzyme and in glycopeptide-dependent mutants (2000), J. Mol. Microbiol. Biotechnol., 2, 321-330.

Search for more literature for 6.3.2.4

Inhibitors

Inhibitors	Comment	Organism	Structure
D-cycloserine	weak inhibition	Enterococcus faecalis
methylphosphinophosphate	strong inhibition	Enterococcus faecalis

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + D-alanine	Enterococcus faecalis	essential enzyme	ADP + phosphate + D-alanyl-D-alanine	-	?

Organism

Organism	UniProt	Comment	Textmining
Enterococcus faecalis	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + D-alanine	-	Enterococcus faecalis	ADP + phosphate + D-alanyl-D-alanine	-	?
ATP + D-alanine	essential enzyme	Enterococcus faecalis	ADP + phosphate + D-alanyl-D-alanine	-	?

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Release 2023.1 (January 2023)