Literature summary for 6.3.2.35 extracted from

Berthet, N.; Perichon, B.; Mazuet, C.; Chapeton-Montes, D.; Bouchier, C.; Bouvet, P.; Legeay, C.; Popoff, M.R.; Courvalin, P.
A vanG-type locus in Clostridium argentinense (2015), J. Antimicrob. Chemother., 70, 1942-1945 .

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Application

Application	Comment	Organism
medicine	emergence of vancomycin resistance in Clostridium argentinense due to decryptification of the vanGCar gene cluster could occur	Clostridium argentinense

Organism

Organism	UniProt	Comment	Textmining
Clostridium argentinense	A0A023J5U9	locus contains genes encoding a carboxypeptidase, a D-alanine:D-serine ligase, a serine transporter and a serine racemase	-
Clostridium argentinense NCIB 10714	A0A023J5U9	locus contains genes encoding a carboxypeptidase, a D-alanine:D-serine ligase, a serine transporter and a serine racemase	-

Synonyms

Synonyms	Comment	Organism
vanGCar	-	Clostridium argentinense

General Information

General Information	Comment	Organism
physiological function	despite the presence of genes vanGCar, Clostridium argentinense NCIB 10714 is susceptible to vancomycin and to teicoplanin. vanGCar is not expressed without or with induction by a subinhibitory concentration of vancomycin	Clostridium argentinense

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Release 2023.1 (January 2023)