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Literature summary for 6.3.2.24 extracted from

  • Kawabata, A.; Muguruma, H.; Tanaka, M.; Takagi, H.
    Kyotorphin synthetase activity in rat adrenal glands and spinal cord (1996), Peptides, 17, 407-411.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
alpha-methyl-L-ornithine
-
Rattus norvegicus
D-arginine
-
Rattus norvegicus
additional information not inhibitory: NG-nitro-L-arginine, N-iminoethyl-L-ornithine Rattus norvegicus
NG-nitro-L-arginine methyl ester
-
Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.03
-
L-tyrosine 37°C, pH 8.0, enzyme from adrenal gland Rattus norvegicus
0.07
-
L-tyrosine 37°C, pH 8.0, enzyme from spinal cord Rattus norvegicus
0.18
-
ATP 37°C, pH 8.0, enzyme from adrenal gland Rattus norvegicus
4.58
-
L-arginine 37°C, pH 8.0, enzyme from spinal cord Rattus norvegicus
7.83
-
L-arginine 37°C, pH 8.0, enzyme from adrenal gland Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble
-
Rattus norvegicus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ Km: 0.15 mM, enzyme from adrenal gland Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
200000 300000 gel filtration, both enzyme from adrenal gland as well as from spinal cord Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland
-
Rattus norvegicus
-
spinal cord
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-tyrosine + L-arginine
-
Rattus norvegicus L-tyrosyl-L-arginine + AMP + diphosphate
-
?