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Literature summary for 6.3.2.11 extracted from

  • Skaper, S.D.; Das, S.; Marshall, F.D.
    Some properties of a homocarnosine-carnosine synthetase isolated from rat brain (1973), J. Neurochem., 21, 1429-1445.
    View publication on PubMed
Search for more literature for 6.3.2.11

Activating Compound

Activating Compound Comment Organism Structure
NAD+
-
 Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required, in equimolar amount with ATP, maximal activity at 4.0-6.0 mM Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-His + 3-amino-n-butanoate
-
 Rattus norvegicus AMP + phosphate + beta-n-aminobutanoyl-L-His
-
 ?
ATP + L-His + beta-Ala
-
 Rattus norvegicus ADP + phosphate + carnosine
-
 ?
CTP + L-His + beta-Ala
-
 Rattus norvegicus CMP + phosphate + carnosine
-
 ?
ITP + L-His + 4-aminobutanoate
-
 Rattus norvegicus IMP + phosphate + homocarnosine
-
 ?
additional information ATP-diphosphate exchange Rattus norvegicus ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 carnosine synthesis Rattus norvegicus

pH Range

pH Minimum pH Maximum Comment Organism
6.3 8.5 6.3: about 70% of maximal activity, 8.5: about 55% of maximal activity Rattus norvegicus