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Literature summary for 6.3.2.11 extracted from

  • Nagai, K.; Niijima, A.; Yamano, T.; Otani, H.; Okumra, N.; Tsuruoka, N.; Nakai, M.; Kiso, Y.
    Possible role of L-carnosine in the regulation of blood glucose through controlling autonomic nerves (2003), Exp. Biol. Med., 228, 1138-1145.
    View publication on PubMed
Search for more literature for 6.3.2.11

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-histidine + beta-alanine + ATP Rattus norvegicus
-
 carnosine + AMP + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 male Winstar rats
-

Purification (Commentary)

Purification (Comment) Organism
partial, using ammonium sulfate precipitation Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
muscle
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 activity in muscle is higher after exercise, which may lead to an increase of the L-carnosine levels in plasma Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-histidine + beta-alanine + ATP
-
 Rattus norvegicus carnosine + AMP + diphosphate
-
 ?

Synonyms

Synonyms Comment Organism
Carnosine synthetase
-
 Rattus norvegicus
Carnosine-anserine synthetase
-
 Rattus norvegicus
Carnosine-homocarnosine synthetase
-
 Rattus norvegicus
Homocarnosine-carnosine synthetase
-
 Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Rattus norvegicus