Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli and Saccharomyces cerevisiae | Crithidia fasciculata |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
gamma-L-Glu-L-Cys-Gly + N1-(gamma-Glu-L-Cys-Gly)-spermidine + ATP | Crithidia fasciculata | synthesis of trypanothione, which is involved in maintaining intracellular thiol redox and in defense against oxidants | N1,N8-bis-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Crithidia fasciculata | O60993 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
gamma-L-Glu-L-Cys-Gly + N1-(gamma-Glu-L-Cys-Gly)-spermidine + ATP | synthesis of trypanothione, which is involved in maintaining intracellular thiol redox and in defense against oxidants | Crithidia fasciculata | N1,N8-bis-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate | - |
? |