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Literature summary for 6.3.1.9 extracted from
- Preparative enzymatic synthesis of trypanothione and trypanothione analogues (2009), Int. J. Parasitol., 39, 1059-1062.
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | production of trypanothione and trypanothione disulfide in >200 mg quantities by mutant C59A lacking the amidase activity. The protocol also allows the synthesis of related glutathione conjugates | Crithidia fasciculata |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| C59A | mutant lacks the amidase activity, while the synthetase activity is similar to wild-type. Constructed for the production of trypanothione and trypanothione disulfide in >200 mg quantities. The protocol also allows the synthesis of related glutathione conjugates | Crithidia fasciculata |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Crithidia fasciculata | - |
- |
- |
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Release 2023.1 (January 2023)
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