Literature summary for 6.3.1.2 extracted from

Harper, C.J.; Hayward, D.; Kidd, M.; Wiid, I.; van Helden, P.
Glutamate dehydrogenase and glutamine synthetase are regulated in response to nitrogen availability in Myocbacterium smegmatis (2010), BMC Microbiol., 10, 138.

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Organism

Organism	UniProt	Comment	Textmining
Mycolicibacterium smegmatis	-	-	-

Synonyms

Synonyms	Comment	Organism
GlnA1	-	Mycolicibacterium smegmatis

Expression

Organism	Comment	Expression
Mycolicibacterium smegmatis	significant up-regulation of glnA1 gene transcription is observed within 0.5 hrs exposure to nitrogen starvation and continues to increase significantly thereafter	up

General Information

General Information	Comment	Organism
metabolism	upon exposure to nitrogen limitation,GS activity increases significantly within 0.5 hrs and continues to increase significantly after 1 hr of nitrogen starvation to reach a final activity at 4 hrs that is approximately 2.5 fold greater than at zero hours. When an ammonium pulse is applied, GS activity decreases significantly within 1 hr of exposure to nitrogen excess	Mycolicibacterium smegmatis

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Release 2023.1 (January 2023)