Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Homo sapiens | 5737 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-glutamate + NH3 | Homo sapiens | - |
ADP + phosphate + L-glutamine | - |
? | |
additional information | Homo sapiens | the enzyme is a target for activation through the signal transducer protein Wnt in the Wnt pathway, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P15104 | french population | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
colon carcinoma cell | - |
Homo sapiens | - |
endocrine gland | - |
Homo sapiens | - |
exocrine gland | - |
Homo sapiens | - |
hepatocyte | - |
Homo sapiens | - |
additional information | expression analysis | Homo sapiens | - |
pancreas | - |
Homo sapiens | - |
pancreatic carcinoma cell | pancreatic endocrine tumor, solid and pseudopapillary neoplasms, the enzyme is overexpressed by 3-13fold in pancreatic tumors compared to healthy tissue, overview | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-glutamate + NH3 | - |
Homo sapiens | ADP + phosphate + L-glutamine | - |
? | |
additional information | the enzyme is a target for activation through the signal transducer protein Wnt in the Wnt pathway, overview | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GLUL | - |
Homo sapiens |
Glutamine synthetase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |