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Literature summary for 6.3.1.2 extracted from

  • Audard, V.; Cavard, C.; Richa, H.; Infante, M.; Couvelard, A.; Sauvanet, A.; Terris, B.; Paye, F.; Flejou, J.F.
    Impaired E-cadherin expression and glutamine synthetase overexpression in solid pseudopapillary neoplasm of the pancreas (2008), Pancreas, 36, 80-83.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Homo sapiens 5737
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-glutamate + NH3 Homo sapiens
-
ADP + phosphate + L-glutamine
-
?
additional information Homo sapiens the enzyme is a target for activation through the signal transducer protein Wnt in the Wnt pathway, overview ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens P15104 french population
-

Source Tissue

Source Tissue Comment Organism Textmining
colon carcinoma cell
-
Homo sapiens
-
endocrine gland
-
Homo sapiens
-
exocrine gland
-
Homo sapiens
-
hepatocyte
-
Homo sapiens
-
additional information expression analysis Homo sapiens
-
pancreas
-
Homo sapiens
-
pancreatic carcinoma cell pancreatic endocrine tumor, solid and pseudopapillary neoplasms, the enzyme is overexpressed by 3-13fold in pancreatic tumors compared to healthy tissue, overview Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-glutamate + NH3
-
Homo sapiens ADP + phosphate + L-glutamine
-
?
additional information the enzyme is a target for activation through the signal transducer protein Wnt in the Wnt pathway, overview Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
GLUL
-
Homo sapiens
Glutamine synthetase
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
Homo sapiens