Inhibitors | Comment | Organism | Structure |
---|---|---|---|
L-glutamine | the enzyme is feedback inhibited | Bacillus subtilis |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Bacillus subtilis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-glutamate + NH3 | Bacillus subtilis | the enzyme is involved in the signal transduction for regulation of the nitrogen metabolism, overview | ADP + phosphate + L-glutamine | - |
? | |
additional information | Bacillus subtilis | the glutamine synthetase transmits the nitrogen regulatory signal to GlnR, a transcription factor involved in nitrogen metabolism regulation, the enzyme interacts with GlnR via the factor's C-terminal autoinhibitory domain, the protein-protein interaction of GlnR and glutamine synthetase stabilizes the GlnR-DNA complexes, interaction analysis of enzyme with wild-type and truncated GlnR proteins, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus subtilis | - |
gene glnA | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-glutamate + NH3 | - |
Bacillus subtilis | ADP + phosphate + L-glutamine | - |
? | |
ATP + L-glutamate + NH3 | the enzyme is involved in the signal transduction for regulation of the nitrogen metabolism, overview | Bacillus subtilis | ADP + phosphate + L-glutamine | - |
? | |
additional information | the glutamine synthetase transmits the nitrogen regulatory signal to GlnR, a transcription factor involved in nitrogen metabolism regulation, the enzyme interacts with GlnR via the factor's C-terminal autoinhibitory domain, the protein-protein interaction of GlnR and glutamine synthetase stabilizes the GlnR-DNA complexes, interaction analysis of enzyme with wild-type and truncated GlnR proteins, overview | Bacillus subtilis | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GlnR | - |
Bacillus subtilis |
Glutamine synthetase | - |
Bacillus subtilis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Bacillus subtilis |