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Literature summary for 6.3.1.2 extracted from

  • Colanduoni, J.A.; Villafranca, J.J.
    Inhibition of Escherichia coli glutamine synthetase by phosphinothricin (1986), Bioorg. Chem., 14, 163-169.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
Phosphinothricin i.e. L-2-amino-4-(hydroxymethyl-phosphinyl)butanoic acid, competitive with respect to Glu, reversible first order inactivation Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
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wild-type and site-directed mutants H4A, H4C, M8L, H12L, H12D
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-Glu + NH4+
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Escherichia coli ADP + phosphate + L-Gln
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