Protein Variants | Comment | Organism |
---|---|---|
I367F | the mutant shows 74% of wild type activity | Methanocaldococcus jannaschii |
I367W | the mutant shows 12% of wild type activity | Methanocaldococcus jannaschii |
I367Y | the mutant shows 13% of wild type activity | Methanocaldococcus jannaschii |
R177K | the mutant shows 5% of wild type activity | Methanocaldococcus jannaschii |
R177M | the mutant shows 7% of wild type activity | Methanocaldococcus jannaschii |
R278A | the mutant shows 66% of wild type activity | Methanocaldococcus jannaschii |
R278D | the mutant shows 39% of wild type activity | Methanocaldococcus jannaschii |
R278K | the mutant shows 104% of wild type activity | Methanocaldococcus jannaschii |
R86A | the mutant shows 27% of wild type activity | Methanocaldococcus jannaschii |
R86K | the mutant shows 10% of wild type activity | Methanocaldococcus jannaschii |
R86M | the mutant shows 16% of wild type activity | Methanocaldococcus jannaschii |
T154A | the mutant shows 4% of wild type activity | Methanocaldococcus jannaschii |
T366F | the mutant shows 62% of wild type activity | Methanocaldococcus jannaschii |
W180F | the mutant shows 25% of wild type activity | Methanocaldococcus jannaschii |
W180V | the mutant shows 25% of wild type activity | Methanocaldococcus jannaschii |
W303A | the mutant shows 30% of wild type activity | Methanocaldococcus jannaschii |
Y143A | the mutant shows 52% of wild type activity | Methanocaldococcus jannaschii |
Y143F | the mutant shows 105% of wild type activity | Methanocaldococcus jannaschii |
Y143L | the mutant shows 57% of wild type activity | Methanocaldococcus jannaschii |
Y66A | the mutant shows 19% of wild type activity | Methanocaldococcus jannaschii |
Y66F | the mutant shows 31% of wild type activity | Methanocaldococcus jannaschii |
Y66G | the mutant shows 30% of wild type activity | Methanocaldococcus jannaschii |
Y66L | the mutant shows 23% of wild type activity | Methanocaldococcus jannaschii |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0599 | - |
GGRLGFYGYDLQD | at pH 7.5 and 37°C | Methanocaldococcus jannaschii |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Methanocaldococcus jannaschii |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + sulfide + [methyl-coenzyme M reductase alpha-subunit McrA]-glycine | Methanocaldococcus jannaschii | - |
ADP + phosphate + [methyl-coenzyme M reductase alpha-subunit McrA]-thioglycine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Methanocaldococcus jannaschii | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + sulfide + GGRLGFYGYDLQD | - |
Methanocaldococcus jannaschii | ADP + phosphate + GGRLGFY(thioglycine)YDLQD | - |
? | |
ATP + sulfide + [methyl-coenzyme M reductase alpha-subunit McrA]-glycine | - |
Methanocaldococcus jannaschii | ADP + phosphate + [methyl-coenzyme M reductase alpha-subunit McrA]-thioglycine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ycaO | - |
Methanocaldococcus jannaschii |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.053 | - |
GGRLGFYGYDLQD | at pH 7.5 and 37°C | Methanocaldococcus jannaschii |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.89 | - |
GGRLGFYGYDLQD | at pH 7.5 and 37°C | Methanocaldococcus jannaschii |