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Literature summary for 6.2.1.51 extracted from

  • Vergnolle, O.; Chavadi, S.S.; Edupuganti, U.R.; Mohandas, P.; Chan, C.; Zeng, J.; Kopylov, M.; Angelo, N.G.; Warren, J.D.; Soll, C.E.; Quadri, L.E.
    Biosynthesis of cell envelope-associated phenolic glycolipids in Mycobacterium marinum (2015), J. Bacteriol., 197, 1040-1050.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mycobacterium marinum B2HIL4
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-
Mycobacterium marinum ATCC BAA-535 B2HIL4
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 17-(4-hydroxyphenyl)heptadecanoate
-
Mycobacterium marinum diphosphate + 17-(4-hydroxyphenyl)heptadecanoyl adenylate
-
?
ATP + 17-(4-hydroxyphenyl)heptadecanoate
-
Mycobacterium marinum ATCC BAA-535 diphosphate + 17-(4-hydroxyphenyl)heptadecanoyl adenylate
-
?
ATP + 19-(4-hydroxyphenyl)nonadecanoate
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Mycobacterium marinum diphosphate + 19-(4-hydroxyphenyl)nonadecanoyl adenylate
-
?
ATP + 19-(4-hydroxyphenyl)nonadecanoate
-
Mycobacterium marinum ATCC BAA-535 diphosphate + 19-(4-hydroxyphenyl)nonadecanoyl adenylate
-
?

General Information

General Information Comment Organism
physiological function the transfer of the iterative biosynthetic intermediates (4-hydroxyphenylalkanoates) synthesized by the polyketide synthase Pks15/1 to the noniterative polyketide synthase PpsA for acyl chain extension is dependent on 4-hydroxyphenylalkanoyl-AMP ligase FadD29 Mycobacterium marinum