Literature summary for 6.2.1.48 extracted from

Bernal, V.; Masdemont, B.; Arense, P.; Canovas, M.; Iborra, J.L.
Redirecting metabolic fluxes through cofactor engineering: Role of CoA-esters pool during L(-)-carnitine production by Escherichia coli (2007), J. Biotechnol., 132, 110-117.

Search for more literature for 6.2.1.48

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	P31552	-	-

General Information

General Information	Comment	Organism
physiological function	the overexpression of CaiB (CoA-transferase) and CaiC (CoA-ligase) leads to an increase in L-carnitine production. Under optimal concentrations of inducer and fumarate (used as electron acceptors), yields reach 10- and 50fold, respectively, that obtained for the wild type strain. Low levels of coenzyme A limits the activity of these two enzymes	Escherichia coli

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)