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Literature summary for 6.2.1.3 extracted from
- Evidence for an essential role of long chain acyl-CoA synthetase in animal cell proliferation. Inhibition of long chain acyl-CoA synthetase by triacsins caused inhibition of Raji cell proliferation (1991), J. Biol. Chem., 266, 4214-4219.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Triacsins | hierarchy of inhibitory potency in decreasing order: triacsin C, triacsin A, triacsin D/ triacsin B | Homo sapiens |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + long-chain carboxylic acid + CoA | Homo sapiens | essential role in animal cell proliferation | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| RAJI cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + long-chain carboxylic acid + CoA | essential role in animal cell proliferation | Homo sapiens | ? | - |
? | |
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