Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Triacsin C | i.e. 1-hydroxy-3-(E,E,E-2',4',7'-undecatrienylidine)triazene, potent competitive inhibitor | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Homo sapiens | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a long-chain fatty acid + CoA | Homo sapiens | - |
AMP + diphosphate + a long-chain fatty acyl-CoA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
enterocyte | highest expression level in enterocytes at the villus tip | Homo sapiens | - |
small intestine | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a long-chain fatty acid + CoA | - |
Homo sapiens | AMP + diphosphate + a long-chain fatty acyl-CoA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ACSL5 | - |
Homo sapiens |
acyl-CoA synthetase 5 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | adenocarcinomas with an invasive phenotype and enhanced proliferation show decreased levels of isoform ACSL5 | down |
General Information | Comment | Organism |
---|---|---|
metabolism | acyl-CoA synthetase 5 plays a key role in fatty acid metabolism. Isoform ACSL5 plays a role in channelling fatty acids towards palmitoylation and other lipid functions with high relevance for cellular behaviour | Homo sapiens |