Cloned (Comment) | Organism |
---|---|
expressed in a yeast fat1DELTA mutant which is deficient in both very-long-chain acyl-CoA synthetase activity and exogenous fatty acid uptake | Arabidopsis thaliana |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + Bodipy-C16 + CoA | - |
Arabidopsis thaliana | ? | - |
? | |
ATP + C1-Bodipy-C12 + CoA | - |
Arabidopsis thaliana | ? | - |
? | |
additional information | Arabidopsis isoforms LACS1-3 display broad substrate specificities, ranging from saturated and monounsaturated C16, C18 and C20 fatty acids to saturated very-long-chain fatty acids | Arabidopsis thaliana | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
FATP | - |
Arabidopsis thaliana |
fatty acid transport protein | - |
Arabidopsis thaliana |
LACS1 | isoform | Arabidopsis thaliana |
LACS2 | isoform | Arabidopsis thaliana |
LACS3 | isoform | Arabidopsis thaliana |
long-chain acyl-CoA synthetase | - |
Arabidopsis thaliana |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Arabidopsis thaliana |
General Information | Comment | Organism |
---|---|---|
physiological function | Arabidopsis long-chain acyl-CoA synthetase isoforms LACS1, LACS2, and LACS3 facilitate fatty acid uptake in yeast. Expression of each isoform in yeast results in uptake of the long-chain fatty acid analogue, C1-Bodipy-C12. Only expression of LACS1 results in uptake of the very-long-chain fatty acid analogue, Bodipy-C16 | Arabidopsis thaliana |